In vitro characterization of xeno-free clinically relevant human collagen and its applicability in cell-laden 3D bioprinting
Schmitt T, Kajave N, Cai HH, Gu L, Albanna M, Kishore V. Journal of Biomaterials Applications. 2021;35(8):912-923. doi:10.1177/0885328220959162
Researchers compared the physical and chemical properties of human collagen hydrogels with those derived from bovine collagen. Results showed that the polymerization rate and compressive modulus of human collagen increased significantly with an increase in concentration. Findings suggest that human-derived collagen may be a viable alternative to xenogenic sources for 3D bioprinting of clinically relevant scaffolds in tissue engineering applications.
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